Anesthesiology· 2015Q1· Review
Clinical Electroencephalography for Anesthesiologists
- 839citations
- Q1SCImago
- 2015year
Short summary
Current depth-of-anesthesia monitoring indices assume uniform brain states across anesthetics, but this review reveals distinct electroencephalogram (EEG) signatures for different drugs, indicating varied neural circuit engagement.
AI-generated from the title and abstract; the full text is not read.
Key points
- Standard EEG indices for anesthesia depth may not be universally applicable.
- Different anesthetics (propofol, dexmedetomidine, ketamine, sevoflurane, isoflurane, desflurane, nitrous oxide) induce unique EEG signatures.
- These distinct signatures reflect varied molecular targets and neural circuit engagement.
- Raw EEG and spectrogram analysis can reveal these drug-specific brain states.
AI-generated from the title and abstract; the full text is not read.
Abstract
AbstractAbstract The widely used electroencephalogram-based indices for depth-of-anesthesia monitoring assume that the same index value defines the same level of unconsciousness for all anesthetics. In contrast, we show that different anesthetics act at different molecular targets and neural circuits to produce distinct brain states that are readily visible in the electroencephalogram. We present a two-part review to educate anesthesiologists on use of the unprocessed electroencephalogram and its spectrogram to track the brain states of patients receiving anesthesia care. Here in part I, we review the biophysics of the electroencephalogram and the neurophysiology of the electroencephalogram signatures of three intravenous anesthetics: propofol, dexmedetomidine, and ketamine, and four inhaled anesthetics: sevoflurane, isoflurane, desflurane, and nitrous oxide. Later in part II, we discuss patient management using these electroencephalogram signatures. Use of these electroencephalogram signatures suggests a neurophysiologically based paradigm for brain state monitoring of patients receiving anesthesia care. The authors review the neurophysiology of the electroencephalogram signatures of the anesthetics: propofol, dexmedetomidine, ketamine, sevoflurane, isoflurane, desflurane, and nitrous oxide. These signatures provide a neurophysiologically based paradigm for brain state monitoring of patients receiving anesthesia care.
The authors' abstract, as published at the source. Anesthesiology, 2015 · DOI ↗
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Field: Anesthesiology and Pain Medicine
Anesthesiology and Pain MedicineMedicine