Briefings in Bioinformatics· 2023Q1· Review
Network pharmacology: towards the artificial intelligence-based precision traditional Chinese medicine
- 613citations
- Q1SCImago
- 2023year
Short summary
This review outlines how artificial intelligence (AI) methods are advancing traditional Chinese medicine network pharmacology (TCM-NP) to uncover complex disease mechanisms from omics data.
AI-generated from the title and abstract; the full text is not read.
Key points
- AI methods are crucial for advancing TCM network pharmacology (TCM-NP) to analyze massive omics data.
- AI applications in TCM-NP are categorized into network relationship mining, network target positioning, and network target navigating.
- TCM-NP, aided by AI, is being applied to understand the biological basis and clinical value of Cold/Hot syndromes.
- The review provides an overview of methodological progress in NP and its AI-driven applications in TCM.
AI-generated from the title and abstract; the full text is not read.
Abstract
Network pharmacology (NP) provides a new methodological perspective for understanding traditional medicine from a holistic perspective, giving rise to frontiers such as traditional Chinese medicine network pharmacology (TCM-NP). With the development of artificial intelligence (AI) technology, it is key for NP to develop network-based AI methods to reveal the treatment mechanism of complex diseases from massive omics data. In this review, focusing on the TCM-NP, we summarize involved AI methods into three categories: network relationship mining, network target positioning and network target navigating, and present the typical application of TCM-NP in uncovering biological basis and clinical value of Cold/Hot syndromes. Collectively, our review provides researchers with an innovative overview of the methodological progress of NP and its application in TCM from the AI perspective.
The authors' abstract, as published at the source. Briefings in Bioinformatics, 2023 · DOI ↗
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Field: Complementary and alternative medicine
Complementary and alternative medicineMedicine