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Science Translational Medicine· 2017Q1

Antimicrobials from human skin commensal bacteria protect against <i>Staphylococcus aureus</i> and are deficient in atopic dermatitis

Teruaki Nakatsuji, Tiffany H. Chen, Saisindhu Narala, Kimberly Chun et al.

Short summary

Skin bacteria naturally produce antimicrobials that defend against harmful pathogens like Staphylococcus aureus. This defense is significantly reduced in individuals with atopic dermatitis.

AI-generated from the title and abstract; the full text is not read.

Key points

  • Skin commensal bacteria produce antimicrobials that inhibit Staphylococcus aureus growth.
  • Atopic dermatitis patients show a deficiency in these protective antimicrobial compounds.
  • Dysbiosis of the skin microbiome contributes to disease development.

AI-generated from the title and abstract; the full text is not read.

Abstract

These findings show how commensal skin bacteria protect against pathogens and demonstrate how dysbiosis of the skin microbiome can lead to disease.

The authors' abstract, as published at the source. Science Translational Medicine, 2017 · DOI ↗

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Field: Dermatology

DermatologyMedicine