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New England Journal of Medicine· 2018Q1

A Randomized Trial of Epinephrine in Out-of-Hospital Cardiac Arrest

Gavin D. Perkins, Chen Ji, Charles D. Deakin, Tom Quinn et al.

Short summary

Epinephrine administration in out-of-hospital cardiac arrest (OHCA) increased 30-day survival by 3.2% vs. placebo (3.2% vs 2.4%, P=0.02), but did not improve favorable neurologic outcomes, with more survivors experiencing severe impairment (31.0% vs 17.8%).

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Field: Emergency Medicine

Emergency MedicineMedicine