PLoS Pathogens· 2014Q1
HIV-Infected Individuals with Low CD4/CD8 Ratio despite Effective Antiretroviral Therapy Exhibit Altered T Cell Subsets, Heightened CD8+ T Cell Activation, and Increased Risk of Non-AIDS Morbidity and Mortality
- 617citations
- Q1SCImago
- 2014year
Short summary
HIV-infected individuals on effective antiretroviral therapy (ART) with a persistently low CD4/CD8 ratio (even with normalized CD4 counts) show skewed T cell subsets, heightened CD8+ T cell activation, and a higher risk of non-AIDS related morbidity and mortality.
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