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New England Journal of Medicine· 2013Q1

Saxagliptin and Cardiovascular Outcomes in Patients with Type 2 Diabetes Mellitus

Benjamin M. Scirica, Deepak L. Bhatt, Eugene Braunwald, Philippe Gabríel Steg et al.

Short summary

Saxagliptin, a DPP-4 inhibitor, did not increase or decrease ischemic cardiovascular events (MI, stroke, CV death) in patients with type 2 diabetes, but it did increase heart failure hospitalizations (3.5% vs 2.8%).

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Field: Endocrinology, Diabetes and Metabolism

Endocrinology, Diabetes and MetabolismMedicine