New England Journal of Medicine· 2014Q1

Spironolactone for Heart Failure with Preserved Ejection Fraction

Bertram Pitt, Marc A. Pfeffer, Susan F. Assmann, Robin Boineau et al.

2,738citations
Q1SCImago
2014year

Short summary

Spironolactone did not significantly reduce the composite outcome of cardiovascular death, aborted cardiac arrest, or heart failure hospitalization in patients with heart failure and preserved ejection fraction (18.6% vs. 20.4%, HR 0.89, P=0.14).

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Field: Endocrinology, Diabetes and Metabolism

Endocrinology, Diabetes and MetabolismMedicine