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New England Journal of Medicine· 2020Q1

Effect of Finerenone on Chronic Kidney Disease Outcomes in Type 2 Diabetes

George L. Bakris, Rajiv Agarwal, Stefan D. Anker, Bertram Pitt et al.

Short summary

In patients with type 2 diabetes and chronic kidney disease (CKD), finerenone significantly reduced the risk of kidney failure, sustained eGFR decrease, or death from renal causes by 17.8% compared to placebo over a median 2.6-year follow-up (HR 0.82, P=0.001). Cardiovascular events were also reduced.

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Field: Endocrinology, Diabetes and Metabolism

Endocrinology, Diabetes and MetabolismMedicine