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The Journal of Clinical Endocrinology & Metabolism· 2014Q1· Guideline

Acromegaly: An Endocrine Society Clinical Practice Guideline

Laurence Katznelson, Edward R. Laws, Шломо Мелмед, Mark E. Molitch et al.

Short summary

The Endocrine Society and European Society of Endocrinology released evidence-based clinical practice guidelines for acromegaly, detailing biochemical assessment, therapeutic algorithms (including medical monotherapy or combination therapy), and pregnancy management.

AI-generated from the title and abstract; the full text is not read.

Key points

  • Developed using the GRADE system to assess evidence quality and recommendation strength.
  • Provides a structured approach to biochemical assessment for acromegaly.
  • Outlines a therapeutic algorithm for acromegaly management, including medical monotherapy and combination therapy.
  • Includes specific recommendations for managing acromegaly during pregnancy.

AI-generated from the title and abstract; the full text is not read.

Abstract

OBJECTIVE: The aim was to formulate clinical practice guidelines for acromegaly. PARTICIPANTS: The Task Force included a chair selected by the Endocrine Society Clinical Guidelines Subcommittee (CGS), five experts in the field, and a methodologist. The authors received no corporate funding or remuneration. This guideline is cosponsored by the European Society of Endocrinology. EVIDENCE: This evidence-based guideline was developed using the Grading of Recommendations, Assessment, Development, and Evaluation (GRADE) system to describe both the strength of recommendations and the quality of evidence. The Task Force reviewed primary evidence and commissioned two additional systematic reviews. CONSENSUS PROCESS: One group meeting, several conference calls, and e-mail communications enabled consensus. Committees and members of the Endocrine Society and the European Society of Endocrinology reviewed drafts of the guidelines. CONCLUSIONS: Using an evidence-based approach, this acromegaly guideline addresses important clinical issues regarding the evaluation and management of acromegaly, including the appropriate biochemical assessment, a therapeutic algorithm, including use of medical monotherapy or combination therapy, and management during pregnancy.

The authors' abstract, as published at the source. The Journal of Clinical Endocrinology & Metabolism, 2014 · DOI ↗

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Field: Endocrinology, Diabetes and Metabolism

Endocrinology, Diabetes and MetabolismMedicine