New England Journal of Medicine· 2015Q1
Glioma Groups Based on 1p/19q,<i>IDH</i>, and<i>TERT</i>Promoter Mutations in Tumors
- 1,988citations
- Q1SCImago
- 2015year
Short summary
Gliomas can be classified into five distinct molecular groups based on three key genetic alterations: TERT promoter mutations, IDH mutations, and 1p/19q codeletion. These groups exhibit significant differences in age at diagnosis, overall survival, and associations with inherited genetic predispositions.
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GeneticsMedicine