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New England Journal of Medicine· 2014Q1· Clinical trial

Fibrinolysis for Patients with Intermediate-Risk Pulmonary Embolism

Guy Meyer, Éric Vicaut, Thierry Danays, Giancarlo Agnelli et al.

Short summary

In intermediate-risk pulmonary embolism patients, tenecteplase plus heparin significantly reduced death or hemodynamic decompensation by 7 days (2.6% vs. 5.6%) compared to placebo, but increased major hemorrhage and stroke risk.

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Field: Internal Medicine

Internal MedicineMedicine