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New England Journal of Medicine· 2019Q1

Rivaroxaban for Thromboprophylaxis in High-Risk Ambulatory Patients with Cancer

Alok A. Khorana, Gerald A. Soff, Ajay K. Kakkar, Saroj Vadhan‐Raj et al.

Short summary

In high-risk ambulatory cancer patients, daily rivaroxaban (10 mg) did not significantly lower the incidence of venous thromboembolism (VTE) or VTE-related death over 180 days compared to placebo (6.0% vs. 8.8%, P=0.10). However, during the intervention period, rivaroxaban showed a substantially lower incidence of these events (2.6% vs. 6.4%).

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Field: Internal Medicine

Internal MedicineMedicine