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Cell Research· 2020Q1

Remdesivir and chloroquine effectively inhibit the recently emerged novel coronavirus (2019-nCoV) in vitro

Manli Wang, Ruiyuan Cao, Leike Zhang, Xing‐Lou Yang et al.

Short summary

Remdesivir and chloroquine have demonstrated in vitro efficacy against the novel coronavirus (2019-nCoV), suggesting potential therapeutic options.

AI-generated from the title and abstract; the full text is not read.

Key points

  • Remdesivir and chloroquine show in vitro inhibition of 2019-nCoV.
  • The novel coronavirus (2019-nCoV) is closely related to SARS-CoV.
  • No specific treatments currently exist for 2019-nCoV.
  • Identification of effective antiviral agents is urgently needed.

AI-generated from the title and abstract; the full text is not read.

Abstract

In December 2019, a novel pneumonia caused by a previously
\nunknown pathogen emerged in Wuhan, a city of 11 million
\npeople in central China. The initial cases were linked to
\nexposures in a seafood market in Wuhan.1 As of January 27,
\n2020, the Chinese authorities reported 2835 confirmed cases in
\nmainland China, including 81 deaths. Additionally, 19 confirmed
\ncases were identified in Hong Kong, Macao and Taiwan, and 39
\nimported cases were identified in Thailand, Japan, South Korea,
\nUnited States, Vietnam, Singapore, Nepal, France, Australia
\nand Canada. The pathogen was soon identified as a novel
\ncoronavirus (2019-nCoV), which is closely related to sever acute
\nrespiratory syndrome CoV (SARS-CoV).2 Currently, there is no
\nspecific treatment against the new virus. Therefore, identifying
\neffective antiviral agents to combat the disease is urgently
\nneeded.

The authors' abstract, as published at the source. Cell Research, 2020 · DOI ↗

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Field: Infectious Diseases

Infectious DiseasesMedicine