Science Translational Medicine· 2012Q1· Review
Hidden Killers: Human Fungal Infections
- 4,340citations
- Q1SCImago
- 2012year
Short summary
Human fungal infections are a major, underappreciated cause of illness and death, particularly in immunocompromised individuals, yet research into diagnostics, drugs, and vaccines lags significantly.
AI-generated from the title and abstract; the full text is not read.
Key points
- Fungal infections cause significant human illness and death.
- The impact of fungal diseases on human health is not widely appreciated.
- Research on diagnostics, drugs, and vaccines for fungal infections is urgently needed.
- Combating invasive fungal infections, particularly in immunocompromised individuals, presents major challenges.
AI-generated from the title and abstract; the full text is not read.
Abstract
Although fungal infections contribute substantially to human morbidity and mortality, the impact of these diseases on human health is not widely appreciated. Moreover, despite the urgent need for efficient diagnostic tests and safe and effective new drugs and vaccines, research into the pathophysiology of human fungal infections lags behind that of diseases caused by other pathogens. In this Review, we highlight the importance of fungi as human pathogens and discuss the challenges we face in combating the devastating invasive infections caused by these microorganisms, in particular in immunocompromised individuals.
The authors' abstract, as published at the source. Science Translational Medicine, 2012 · DOI ↗
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Field: Infectious Diseases
Infectious DiseasesMedicine