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Clinical Microbiology Reviews· 2022Q1· Review

Updated Review on<i>Nocardia</i>Species: 2006–2021

Rita M. Traxler, Melissa E. Bell, Brent A. Lasker, Brendan Headd et al.

Short summary

This review updates the understanding of Nocardia species, incorporating taxonomic changes and the impact of new technologies like MALDI-TOF and whole genome sequencing on diagnosis and treatment.

AI-generated from the title and abstract; the full text is not read.

Key points

  • Significant taxonomic expansion of the Nocardia genus since 2006.
  • New technologies like MALDI-TOF and whole genome sequencing are transforming Nocardia diagnosis.
  • Updated insights into clinical manifestations, epidemiology, and geographic distribution.
  • Includes a new section on actinomycotic mycetoma.

AI-generated from the title and abstract; the full text is not read.

Abstract

review by Brown-Elliott et al. published in 2006 (B. A. Brown-Elliott, J. M. Brown, P. S. Conville, and R. J. Wallace. Jr., Clin Microbiol Rev 19:259-282, 2006, https://doi.org/10.1128/CMR.19.2.259-282.2006). Included is a discussion on the taxonomic expansion of the genus, current identification methods, and the impact of new technology (including matrix-assisted laser desorption ionization-time of flight [MALDI-TOF] and whole genome sequencing) on diagnosis and treatment. Clinical manifestations, the epidemiology, and geographic distribution are briefly discussed. An additional section on actinomycotic mycetoma is added to address this often-neglected disease.

The authors' abstract, as published at the source. Clinical Microbiology Reviews, 2022 · DOI ↗

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Field: Microbiology

MicrobiologyMedicine