Medicine & Science in Sports & Exercise· 2001Q1
Effects of resistance exercise and creatine supplementation on myasthenia gravis: a case study
- 37citations
- Q1SCImago
- 2001year
Short summary
A 15-week regimen of resistance exercise plus creatine supplementation increased body weight by 6.8%, fat-free mass by 4.3%, and peak strength in leg extension by 37.0% and leg flexion by 12.5% in a single patient with myasthenia gravis.
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Key points
- A 15-week resistance exercise and creatine supplementation protocol was tested on one patient with myasthenia gravis.
- Body weight increased by 6.8% and fat-free mass by 4.3%.
- Peak strength for leg extension increased by 37.0% and leg flexion by 12.5%.
- Blood chemistry remained within normal limits during the intervention.
AI-generated from the title and abstract; the full text is not read.
Abstract
PURPOSE: The purpose of this case study was to determine the effects of 15 wk of resistance exercise and creatine (Cr) supplementation on body composition, training volume, peak strength, and complete blood chemistry in a patient with myasthenia gravis (MG). METHODS: The patient was a 26-yr-old man who was taking prednisone and azathioprine for his condition. The patient self-administered 5 g of Cr per day in addition to resistance exercise 3 times per week. Fasting blood samples were obtained and body weight (BW) and fat free mass (FFM; via hydrostatic weighing) were measured before and after training and Cr supplementation. In addition, isokinetic (Cybex II) peak strength for leg extension (LE), leg flexion (LF), and volume load (repetition x mass lifted) for the first and last resistance training session were determined. RESULTS: After Cr supplementation and training, the results demonstrated increases in BW (6.8%), FFM (4.3%), upper body volume load (37.0%), lower body volume load (15.0%), and peak strength for LE (37.0%) and LF (12.5%). Moreover, blood chemistry values remained within normal limits for the duration of the 15-wk study. CONCLUSION: These data suggest that resistance exercise plus Cr supplementation may promote gains in strength and FFM in patients with MG.
The authors' abstract, as published at the source. Medicine & Science in Sports & Exercise, 2001 · DOI ↗
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