Journal of Neurochemistry· 2016Q1· Review
The clinical symptoms of Parkinson's disease
- 1,396citations
- Q1SCImago
- 2016year
Short summary
Parkinson's disease (PD) is a slowly progressing neurodegenerative disorder characterized by both motor symptoms (slow movement, tremor, gait/balance issues) and a wide range of non-motor symptoms including autonomic dysfunction, sleep disorders, and neuropsychiatric issues.
AI-generated from the title and abstract; the full text is not read.
Key points
- Parkinson's disease presents with both motor and non-motor symptoms.
- Motor symptoms include impaired motor function, slow movements, tremor, and gait/balance disturbances.
- Non-motor symptoms are common and include autonomic dysfunction (orthostatic hypotension, constipation, urinary issues), sleep disorders, and neuropsychiatric symptoms.
- The article describes these symptoms in the context of disease progression.
AI-generated from the title and abstract; the full text is not read.
Abstract
In this review, the clinical features of Parkinson's disease, both motor and non-motor, are described in the context of the progression of the disease. Also briefly discussed are the major treatment strategies and their complications. Parkinson's disease is a slowly progressing neurodegenerative disorder, causing impaired motor function with slow movements, tremor and gait and balance disturbances. A variety of non-motor symptoms are common in Parkinson's disease. They include disturbed autonomic function with orthostatic hypotension, constipation and urinary disturbances, a variety of sleep disorders and a spectrum of neuropsychiatric symptoms. This article describes the different clinical symptoms that may occur and the clinical course of the disease. This article is part of a special issue on Parkinson disease.
The authors' abstract, as published at the source. Journal of Neurochemistry, 2016 · DOI ↗
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Field: Neurology (Medicine)
NeurologyMedicine