Science· 2017Q1
Vitamin B <sub>3</sub> modulates mitochondrial vulnerability and prevents glaucoma in aged mice
- 631citations
- Q1SCImago
- 2017year
Short summary
Vitamin B3 (niacin) supplementation prevented glaucoma development and eye degeneration in mice prone to the disease.
AI-generated from the title and abstract; the full text is not read.
Key points
- Vitamin B3 (niacin) supplementation prevented glaucoma in mice.
- Supplementation averted early glaucoma signs in young mice.
- Vitamin B3 halted glaucoma progression in aged mice with existing symptoms.
- The findings suggest a protective role for vitamin B3 in maintaining eyesight.
AI-generated from the title and abstract; the full text is not read.
Abstract
Vitamin B 3 protects mice from glaucoma Glaucoma is the most common cause of age-related blindness in the United States. There is currently no cure, and once vision is lost, the condition is irreversible. Williams et al. now report that vitamin B 3 (also known as niacin) prevents eye degeneration in glaucoma-prone mice (see the Perspective by Crowston and Trounce). Supplementing the diets of young mice with vitamin B 3 averted early signs of glaucoma. Vitamin B 3 also halted further glaucoma development in aged mice that already showed signs of the disease. Thus, healthy intake of vitamin B 3 may protect eyesight. Science , this issue p. 756 ; see also p. 688
The authors' abstract, as published at the source. Science, 2017 · DOI ↗
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Field: Ophthalmology
OphthalmologyMedicine