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Nature· 2012Q1

Comprehensive molecular characterization of human colon and rectal cancer

The Cancer Genome Atlas Network

Short summary

A genome-wide analysis of 276 colorectal cancer samples reveals that 16% are hypermutated, with distinct causes, and identifies 24 significantly mutated genes, including new targets like ERBB2 and IGF2 amplifications.

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Field: Pathology and Forensic Medicine

Pathology and Forensic MedicineMedicine