JAMA· 2013Q1

Prenatal Valproate Exposure and Risk of Autism Spectrum Disorders and Childhood Autism

Jakob Christensen, Therese Koops Grønborg, Merete Juul Sørensen, Diana Schendel et al.

1,365citations
Q1SCImago
2013year

Short summary

Maternal valproate use during pregnancy increased offspring risk of autism spectrum disorder (ASD) by 2.9 times and childhood autism by 5.2 times, even after accounting for maternal epilepsy.

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Field: Pediatrics, Perinatology and Child Health

Pediatrics, Perinatology and Child HealthMedicine