The Lancet· 2018· Review
Comparative Efficacy and Acceptability of 21 Antidepressant Drugs for the Acute Treatment of Adults With Major Depressive Disorder: A Systematic Review and Network Meta-Analysis
- 3,496citations
- 2018year
Short summary
A comprehensive meta-analysis of 522 trials found that while all 21 antidepressants studied were more effective than placebo for acute major depressive disorder, differences in efficacy and acceptability varied significantly, particularly in head-to-head comparisons.
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PharmacologyMedicine