Brain· 2018Q1· Review

The cholinergic system in the pathophysiology and treatment of Alzheimer’s disease

Harald Hampel, M.‐Marsel Mesulam, A. Claudio Cuello, Martin R. Farlow et al.

1,862citations
Q1SCImago
2018year

Short summary

Cholinergic deficits, stemming from neurofibrillary degeneration in the basal forebrain, are central to Alzheimer's disease (AD) pathophysiology, leading to impaired memory and cognition.

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Field: Pharmacology

PharmacologyMedicine