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New England Journal of Medicine· 2014Q1

Two Phase 3 Trials of Bapineuzumab in Mild-to-Moderate Alzheimer's Disease

Stephen Salloway, Reisa A. Sperling, Nick C. Fox, Kaj Blennow et al.

Short summary

Bapineuzumab, an anti-amyloid-beta antibody, failed to show significant clinical benefits in two Phase 3 trials for mild-to-moderate Alzheimer's disease, with no meaningful differences in cognitive or functional scores compared to placebo.

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Field: Psychiatry and Mental health

Psychiatry and Mental healthMedicine