International Journal of Dermatology· 2026Q1
Multiple Agminated Papules on the Face
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- Q1SCImago
- 2026year
Short summary
A rare case of facial pseudolymphoma presented as asymptomatic, grouped papules on a middle-aged man's face.
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Key points
- A middle-aged man presented with asymptomatic, symmetrically grouped papules on his face.
- Histopathology showed peri-follicular B-cell lymphoid aggregates with germinal center formation.
- Immunohistochemistry indicated a reactive lymphoid follicle, suggesting pseudolymphoma.
- The case highlights the importance of combined histopathological and immunohistochemical evaluation for diagnosing rare facial papule presentations.
AI-generated from the title and abstract; the full text is not read.
Abstract
A middle-aged man presented with asymptomatic multiple grouped papules present bilaterally symmetrically on the face. Histopathology revealed peri-follicular, predominantly B-cell lymphoid aggregates with germinal center formation and occasional tingible body macrophages. Immunohistochemistry for Bcl-2 was positive in the peripheral mantle zone while sparing the follicle center, suggesting a reactive lymphoid follicle. Clinical differential diagnosis of facial papules can be broad, encompassing sarcoidosis, granulomatous rosacea, lupus miliaris disseminatus faciei, acneiform eruption, and eruptive benign appendageal tumors, among others. We report a rare case of pseudolymphoma clinically presenting as multiple facial papules, diagnosed through combined histopathological and immunohistochemical evaluation.
The authors' abstract, as published at the source. International Journal of Dermatology, 2026 · DOI ↗
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Field: Dermatology
DermatologyMedicine