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Radiology· 2020Q1

Chest CT for Typical Coronavirus Disease 2019 (COVID-19) Pneumonia: Relationship to Negative RT-PCR Testing

Xingzhi Xie, Zheng Zhong, Wei Zhao, Chao Zheng et al.

Short summary

Chest CT scans revealed typical COVID-19 pneumonia findings (ground-glass opacity and/or consolidation) in five patients who initially tested negative via RT-PCR, with later confirmed infection after repeated testing.

AI-generated from the title and abstract; the full text is not read.

Key points

  • Five patients with COVID-19 infection initially presented with negative RT-PCR results.
  • All five patients showed typical chest CT findings, including ground-glass opacity and/or consolidation.
  • Repeated swab tests eventually confirmed COVID-19 infection in all patients.
  • A combination of repeated RT-PCR tests and CT scanning may aid diagnosis in suspicious cases with initial negative RT-PCR.

AI-generated from the title and abstract; the full text is not read.

Abstract

Some patients with positive chest CT findings may present with negative results of real-time reverse-transcription polymerase chain reaction (RT-PCR) tests for coronavirus disease 2019 (COVID-19). In this study, the authors present chest CT findings from five patients with COVID-19 infection who had initial negative RT-PCR results. All five patients had typical imaging findings, including ground-glass opacity (five patients) and/or mixed ground-glass opacity and mixed consolidation (two patients). After isolation for presumed COVID-19 pneumonia, all patients were eventually confirmed to have COVID-19 infection by means of repeated swab tests. A combination of repeated swab tests and CT scanning may be helpful for individuals with a high clinical suspicion of COVID-19 infection but negative findings at RT-PCR screening.

The authors' abstract, as published at the source. Radiology, 2020 · DOI ↗

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Field: Radiology, Nuclear Medicine and Imaging

Radiology, Nuclear Medicine and ImagingMedicine