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Cancer Epidemiology Biomarkers & Prevention· 2014Q1· Review

Gastric Cancer: Descriptive Epidemiology, Risk Factors, Screening, and Prevention

Parisa Karimi, Farhad Islami, Sharmila Anandasabapathy, Neal D. Freedman et al.

Short summary

Gastric cancer, though declining globally, remains a significant cause of cancer death worldwide, necessitating a review of its epidemiology, risk factors, and prevention strategies.

AI-generated from the title and abstract; the full text is not read.

Key points

  • Gastric cancer incidence has declined globally over the past century but remains a major cause of cancer death.
  • The review covers descriptive epidemiology (incidence, survival, mortality, trends), risk factors (environmental, genetic), and early detection methods.
  • Early detection strategies utilizing serologic markers and precursor lesions are discussed.
  • Prevention strategies and areas for future research are also addressed.

AI-generated from the title and abstract; the full text is not read.

Abstract

Less than a century ago, gastric cancer was the most common cancer in the United States and perhaps throughout the world. Despite its worldwide decline in incidence over the past century, gastric cancer remains a major killer across the globe. This article reviews the epidemiology, screening, and prevention of gastric cancer. We first discuss the descriptive epidemiology of gastric cancer, including its incidence, survival, mortality, and trends over time. Next, we characterize the risk factors for gastric cancer, both environmental and genetic. Serologic markers and histological precursor lesions of gastric cancer and early detection of gastric cancer using these markers are reviewed. Finally, we discuss prevention strategies and provide suggestions for further research.

The authors' abstract, as published at the source. Cancer Epidemiology Biomarkers & Prevention, 2014 · DOI ↗

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Field: Surgery

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