New England Journal of Medicine· 2017Q1

IgG Endopeptidase in Highly Sensitized Patients Undergoing Transplantation

Stanley C. Jordan, Tomas Lorant, Jua Choi, Christian Kjellman et al.

Short summary

An IgG endopeptidase (IdeS) eliminated donor-specific antibodies, enabling kidney transplantation in 24 of 25 highly HLA-sensitized patients.

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TransplantationMedicine