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Journal of Periodontology· 2016Q1

Optimized Platelet‐Rich Fibrin With the Low‐Speed Concept: Growth Factor Release, Biocompatibility, and Cellular Response

Masako Fujioka‐Kobayashi, Richard J. Miron, Maria Hernandez, Umadevi Kandalam et al.

Short summary

Modifying platelet-rich fibrin (PRF) centrifugation speed and time with a low-speed concept (1,300 rpm) significantly increased growth factor release (PDGF, TGF-β1, EGF, IGF) and enhanced human fibroblast migration, proliferation, and collagen mRNA levels compared to standard PRF (2,700 rpm).

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Field: Urology

UrologyMedicine