Science· 2016Q1

Hair follicle aging is driven by transepidermal elimination of stem cells via COL17A1 proteolysis

Hiroyuki Matsumura, Yasuaki Mohri, Nguyễn Thanh Bình, Hironobu Morinaga et al.

399citations
Q1SCImago
2016year

Short summary

Hair follicle stem cell (HFSC) aging, triggered by DNA damage and subsequent proteolysis of COL17A1, leads to HFSC elimination from the skin and hair follicle miniaturization, causing hair loss in mice and humans.

AI-generated from the title and abstract; the full text is not read.

TakeawaysIn the app

Key pointsIn the app

Ask the paperIn the app

The rest is in the Pofolia app

Takeaways, key points and questions to the paper; new summaries every day for your field. Free.

Get it on Google Play Download on the App Store

Field: Urology

UrologyMedicine