PLoS ONE· 2012Q1
Childhood Adversity and Epigenetic Modulation of the Leukocyte Glucocorticoid Receptor: Preliminary Findings in Healthy Adults
- 482citations
- Q1SCImago
- 2012year
Short summary
Childhood adversity, including parental loss and maltreatment, is linked to increased methylation of the NR3C1 gene promoter in leukocytes (p<.05) and attenuated cortisol responses to the Dex/CRH test (p<.05) in healthy adults.
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Behavioral NeuroscienceNeuroscience