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Proceedings of the National Academy of Sciences· 2016Q1

Cluster failure: Why fMRI inferences for spatial extent have inflated false-positive rates

Anders Eklund, Thomas E. Nichols, Hans Knutsson

Short summary

Widely used fMRI analysis software (SPM, FSL, AFNI) inflates false-positive rates for cluster-based spatial inference, with parametric methods being invalid for clusterwise analysis.

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Field: Cognitive Neuroscience

Cognitive NeuroscienceNeuroscience