BMJ· 2026Q1
Starting right: aligning eligibility and treatment assignment at time zero when emulating a target trial
- 30citations
- Q1SCImago
- 2026year
Short summary
This paper provides methodological guidance for emulating target trials using longitudinal observational data, focusing on aligning eligibility criteria and treatment assignment at the start of follow-up to prevent design-induced biases like immortal time and selection bias.
AI-generated from the title and abstract; the full text is not read.
Key points
- Guidance provided for emulating target trials with longitudinal observational data.
- Focus on aligning eligibility criteria and treatment assignment at time zero.
- Aims to prevent design-induced biases like immortal time and selection bias.
AI-generated from the title and abstract; the full text is not read.
Abstract
This article provides methodological guidance when emulating a target trial with longitudinal observational data by showing how to align eligibility criteria and treatment assignment at the start of follow-up to prevent design induced biases, such as immortal time and selection bias.
The authors' abstract, as published at the source. BMJ, 2026 · DOI ↗
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Field: Statistics and Probability
Statistics and ProbabilityMathematics