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Molecular Biology Reports· 2025Q2· Review

Effect of natural compounds on NRF2/KEAP1 signaling in periodontitis: a potential use to prevent age-related disorders

Giovanni Tossetta, Sonia Fantone, Fabiola Olivieri, Roberta Mazzucchelli et al.

Short summary

Activating the NRF2/KEAP1 pathway, which is impaired in periodontitis, may offer a therapeutic strategy for both gum disease and age-related neurodegenerative disorders like Alzheimer's and Parkinson's.

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PeriodonticsDentistry