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Journal of Periodontal Research· 2025Q1· Review

Inflammatory and Immunological Basis of Periodontal Diseases

Giacomo Baima, Marion Arce, Mario Romandini, Thomas E. Van Dyke

Short summary

Periodontitis is fundamentally an immunoinflammatory disorder driven by host-microbiome imbalance, leading to tissue degradation and bone loss. This review reinterprets the classical model of lesion progression through a modern immunological lens.

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PeriodonticsDentistry