PofoliaShared via Pofolia

Radiology· 2026Q1

Quantitative Chest CT–derived Fibrosis and Vascular Remodeling and Acute Exacerbation Risk in Mild Idiopathic Pulmonary Fibrosis

Mi Hyun Yang, Seonok Kim, Sang Min Lee, Jihye Yun et al.

Short summary

Quantitative CT-derived fibrosis burden and vascular remodeling in mild idiopathic pulmonary fibrosis are linked to acute exacerbation risk, with venous and arterial remodeling mediating fibrosis effects.

AI-generated from the title and abstract; the full text is not read.

Key points

  • Quantitative CT-derived fibrosis burden is associated with acute exacerbation risk in mild IPF.
  • Vascular remodeling, including venous and arterial changes, is also linked to acute exacerbation risk.
  • Venous and arterial remodeling mediate the effect of fibrosis on exacerbation risk.
  • Vascular metrics derived from CT scans can aid in risk stratification for patients with mild IPF.

AI-generated from the title and abstract; the full text is not read.

Abstract

In mild idiopathic pulmonary fibrosis, quantitative CT–derived fibrosis burden and vascular remodeling were associated with acute exacerbation risk, with venous and arterial remodeling mediating fibrosis effects, supporting the value of vascular metrics for risk stratification.

The authors' abstract, as published at the source. Radiology, 2026 · DOI ↗

TakeawaysPremium
Ask the paperFree account

Continue with a free account

Ask the paper: 3 free questions a day about this paper; save it, get its citation, new summaries every day for your field. Takeaways are Premium.

Continue free on the web

Sign in with Google or Apple; no card needed. You come back to this paper.

On your phone:

Field: Pulmonary and Respiratory Medicine

Pulmonary and Respiratory MedicineMedicine