Key papers in Pulmonary and Respiratory Medicine
Pofolia’s corpus holds 66 papers from the Pulmonary and Respiratory Medicine subfield (2012–2026). The list below starts with the most cited.
Most cited
Ranked by citation count. Because citations accumulate over time, this list naturally leans towards work published a few years ago; for where the field is now, see “recently added”.
Global Strategy for the Diagnosis, Management, and Prevention of Chronic Obstructive Pulmonary Disease
American Journal of Respiratory and Critical Care Medicine · 2012 · Q1 · SJR 5.00 · FWCI 1056.00 · 16,105 citations
The updated GOLD strategy document mandates spirometry for COPD diagnosis and introduces a four-category (A-D) patient assessment based on symptoms, airflow limitation, and exacerbation history.
WHO Classification of Tumours of Haematopoietic and Lymphoid Tissues
Medical Entomology and Zoology · 2017 · FWCI 399.83 · 13,032 citations
This entry is a citation for the WHO Classification of Tumours of Haematopoietic and Lymphoid Tissues, sourced from the Central Library of Tehran University of Medical Sciences.
Aerosol and Surface Stability of SARS-CoV-2 as Compared with SARS-CoV-1
New England Journal of Medicine · 2020 · Q1 · SJR 18.00 · FWCI 1031.28 · 10,226 citations
SARS-CoV-2 remained infectious in aerosols for up to 3 hours and on surfaces for up to 72 hours, similar to SARS-CoV-1.
Acute Respiratory Distress Syndrome
JAMA · 2012 · Q1 · SJR 5.00 · FWCI 263.56 · 8,851 citations
The new Berlin Definition for Acute Respiratory Distress Syndrome (ARDS) offers improved reliability and validity over the previous 1994 definition, classifying ARDS into mild, moderate, and severe categories based on oxygenation levels.
Intratumor Heterogeneity and Branched Evolution Revealed by Multiregion Sequencing
New England Journal of Medicine · 2012 · Q1 · SJR 18.00 · FWCI 510.49 · 7,822 citations · Open access
Multiregion sequencing of renal carcinomas reveals branched tumor evolution where 63-69% of somatic mutations are not uniformly present across the tumor, challenging single-biopsy approaches.
2015 ESC/ERS Guidelines for the diagnosis and treatment of pulmonary hypertension
European Heart Journal · 2015 · Q1 · SJR 5.00 · FWCI 434.68 · 7,001 citations · Open access
These 2015 ESC/ERS Guidelines offer recommendations for diagnosing and treating pulmonary hypertension, based on the scientific and medical knowledge available at the time of publication.
2012 Revised International Chapel Hill Consensus Conference Nomenclature of Vasculitides
Arthritis & Rheumatism · 2012 · FWCI 190.56 · 6,598 citations
This paper presents the revised nomenclature for primary systemic vasculitides, updating the 1994 definitions to reflect advancements in understanding and classification.
Multi-ethnic reference values for spirometry for the 3–95-yr age range: the global lung function 2012 equations
European Respiratory Journal · 2012 · Q1 · SJR 5.00 · FWCI 91.78 · 5,915 citations · Open access
New spirometry prediction equations and lower limits of normal have been derived for individuals aged 3-95 years, applicable globally across major ethnic groups.
Nivolumab versus Everolimus in Advanced Renal-Cell Carcinoma
New England Journal of Medicine · 2015 · Q1 · SJR 18.00 · FWCI 427.90 · 5,913 citations · Open access
Nivolumab significantly improved overall survival by a median of 5.4 months compared to everolimus in patients with advanced renal-cell carcinoma who had received prior treatment.
Epidemiology, Patterns of Care, and Mortality for Patients With Acute Respiratory Distress Syndrome in Intensive Care Units in 50 Countries
JAMA · 2016 · Q1 · SJR 5.00 · FWCI 277.37 · 5,894 citations · Open access
A global study found that Acute Respiratory Distress Syndrome (ARDS) affects 10.4% of ICU admissions, is often underrecognized by clinicians, and is associated with high mortality rates, varying by severity.
Comprehensive molecular profiling of lung adenocarcinoma
Nature · 2014 · Q1 · SJR 19.00 · FWCI 292.86 · 5,870 citations · Open access
Comprehensive molecular profiling of 230 lung adenocarcinomas reveals high somatic mutation rates (mean 8.9 mutations/megabase) and identifies 18 significantly mutated genes, including novel RIT1 and MGA mutations.
Osimertinib in Untreated <i>EGFR</i> -Mutated Advanced Non–Small-Cell Lung Cancer
New England Journal of Medicine · 2017 · Q1 · SJR 18.00 · FWCI 274.30 · 5,313 citations · Open access
In previously untreated patients with EGFR-mutated advanced non-small-cell lung cancer, osimertinib significantly extended progression-free survival by nearly double (18.9 vs. 10.2 months) compared to standard EGFR-TKIs.
Nivolumab plus Ipilimumab versus Sunitinib in Advanced Renal-Cell Carcinoma
New England Journal of Medicine · 2018 · Q1 · SJR 18.00 · FWCI 350.22 · 4,667 citations · Open access
Combining nivolumab and ipilimumab significantly improved overall survival and objective response rates compared to sunitinib in previously untreated advanced renal-cell carcinoma patients with intermediate or poor risk.
Efficacy and Safety of Nintedanib in Idiopathic Pulmonary Fibrosis
New England Journal of Medicine · 2014 · Q1 · SJR 18.00 · FWCI 217.87 · 4,641 citations · Open access
Nintedanib, an inhibitor of multiple tyrosine kinases, significantly slowed lung function decline in patients with idiopathic pulmonary fibrosis by reducing the annual rate of forced vital capacity (FVC) loss by 125.3 ml/year in one trial and 93.7 ml/year in another, compared to placebo.
The Cancer Imaging Archive (TCIA): Maintaining and Operating a Public Information Repository
Journal of Digital Imaging · 2013 · FWCI 22.48 · 4,630 citations · Open access
The Cancer Imaging Archive (TCIA) is an open-source, open-access repository established by the National Cancer Institute to centralize and share cancer-related imaging data, supporting secondary research and educational initiatives.
Increased Survival with Enzalutamide in Prostate Cancer after Chemotherapy
New England Journal of Medicine · 2012 · Q1 · SJR 18.00 · FWCI 256.57 · 4,593 citations · Open access
Enzalutamide significantly extended overall survival by 4.8 months in men with metastatic castration-resistant prostate cancer post-chemotherapy, compared to placebo.
An Official American Thoracic Society/European Respiratory Society Statement: Update of the International Multidisciplinary Classification of the Idiopathic Interstitial Pneumonias
American Journal of Respiratory and Critical Care Medicine · 2013 · Q1 · SJR 5.00 · FWCI 138.17 · 4,295 citations
This statement updates the 2002 classification of idiopathic interstitial pneumonias (IIPs) by incorporating a decade of new research, refining definitions, and introducing new classifications for challenging cases.
Ferroptosis: molecular mechanisms and health implications
Cell Research · 2020 · Q1 · SJR 6.00 · FWCI 152.76 · 4,184 citations · Open access
Ferroptosis, an iron-dependent form of non-apoptotic cell death, is triggered by a redox imbalance involving abnormal activity of enzymes that produce or detoxify free radicals and lipid oxidation products.
Diagnosis of Idiopathic Pulmonary Fibrosis. An Official ATS/ERS/JRS/ALAT Clinical Practice Guideline
American Journal of Respiratory and Critical Care Medicine · 2018 · Q1 · SJR 5.00 · FWCI 259.23 · 4,135 citations
New clinical practice guidelines refine diagnostic criteria for idiopathic pulmonary fibrosis (IPF), updating imaging patterns and specifying when lung biopsies and bronchoalveolar lavage (BAL) are conditionally recommended or strongly advised against.
Ferroptosis: past, present and future
Cell Death and Disease · 2020 · Q1 · SJR 3.00 · FWCI 200.47 · 4,134 citations · Open access
Ferroptosis is a newly discovered, iron-dependent form of cell death characterized by lipid peroxidation and reduced antioxidant capacity. It is increasingly linked to numerous diseases, making its regulation a key area for therapeutic development.
Recently added
Journal of Thoracic Disease
Journal of Thoracic Disease · 2026 · Q2 · 706 citations
The Journal of Thoracic Disease publishes new findings and practical information on the diagnosis and treatment of thoracic conditions.
Ultrasound monitoring respiratory muscle rehabilitation training can promote the recovery of diaphragmatic function in traumatic spinal cord injury (TSCI) patients
European journal of medical research · 2025 · FWCI 1.55 · 2 citations · Open access
Respiratory muscle rehabilitation training, guided by ultrasound, significantly improved diaphragm thickness (2.38 vs. 2.05 mm), movement (1.85 vs. 1.52 mm), and contraction speed (1.45 vs. 1.20 cm/s) in traumatic spinal cord injury (TSCI) patients compared to usual care.
2022 ESC/ERS Guidelines for the diagnosis and treatment of pulmonary hypertension
European Heart Journal · 2022 · Q1 · SJR 5.00 · FWCI 424.84 · 3,719 citations
The 2022 ESC/ERS guidelines introduce a new risk stratification model for pulmonary hypertension (PH) that incorporates clinical, echocardiographic, and biomarkers to predict 1-year mortality, aiming to improve treatment decisions.
Idiopathic Pulmonary Fibrosis (an Update) and Progressive Pulmonary Fibrosis in Adults: An Official ATS/ERS/JRS/ALAT Clinical Practice Guideline
American Journal of Respiratory and Critical Care Medicine · 2022 · Q1 · SJR 5.00 · FWCI 309.65 · 2,671 citations
New guidelines conditionally recommend transbronchial lung cryobiopsy as an alternative to surgical biopsy for IPF and suggest nintedanib for progressive pulmonary fibrosis (PPF) in non-IPF ILDs.
Lutetium-177–PSMA-617 for Metastatic Castration-Resistant Prostate Cancer
New England Journal of Medicine · 2021 · Q1 · SJR 18.00 · FWCI 210.27 · 2,658 citations
Adding lutetium-177–PSMA-617 (Lu-PSMA-617) to standard care significantly improved progression-free survival (PFS) and overall survival (OS) in patients with PSMA-positive metastatic castration-resistant prostate cancer.
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