Clinical & Experimental Allergy· 2026Q2
Yeast Surface Display for Efficient Generation of Nanobody‐Based Human IgG Targeting the 11S Globulin From Hazelnut, Cor a 9
- 0citations
- Q2SCImago
- 2026year
Short summary
Yeast surface display enabled efficient selection of nanobodies and generation of IgG-like antibodies that target the hazelnut allergen Cor a 9, showing cross-reactivity with other tree nuts and peanut, but not walnut.
AI-generated from the title and abstract; the full text is not read.
Key points
- Yeast surface display was used to select nanobodies targeting the hazelnut allergen Cor a 9.
- Nanobodies were successfully engineered into IgG-like antibody formats.
- The generated antibodies cross-react with other tree nuts and peanut.
- No cross-reactivity was observed with walnut.
AI-generated from the title and abstract; the full text is not read.
Abstract
Summary Yeast surface display allows efficient selection of nanobodies and generation of IgG‐like antibody formats. Antibodies targeting Cor a 9 exhibit cross‐reactivity with tree nuts and peanut, not walnut.
The authors' abstract, as published at the source. Clinical & Experimental Allergy, 2026 · DOI ↗
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Field: Immunology and Allergy
Immunology and AllergyMedicine