Chinese Journal of Pharmaceuticals· 2011
Determination of Amlodipine Besylate and Valsartan in Compound Valsartan Tablets by HPLC
- 0citations
- 2011year
Short summary
An HPLC method accurately quantifies amlodipine besylate (3-7 μg/ml range) and valsartan (48-112 μg/ml range) in compound valsartan tablets with average recoveries of 99.8% and 99.6%, respectively.
AI-generated from the title and abstract; the full text is not read.
Key points
- Developed an HPLC method for simultaneous determination of amlodipine besylate and valsartan.
- Method uses a C18 column with a mobile phase of potassium dihydrogen phosphate and methanol.
- Linearity was established for amlodipine besylate (3-7 μg/ml) and valsartan (48-112 μg/ml).
- Achieved high average recoveries (99.8% and 99.6%) with low RSDs (1.43% and 1.02%).
AI-generated from the title and abstract; the full text is not read.
Abstract
An HPLC method was established for the determination of amlodipine besylate and valsartan in the compound valsartan tablets.A C18 column was used with the mobile phase of 0.03 mol/L potassium dihydrogen phosphate solution(adjusted to pH 3.0 with 85% phosphoric acid)-methanol(40︰60) at the detection wavelength of 237 nm.The calibration curves of amlodipine besylate and valsartan were linear in the ranges of 3-7 and 48-112 μg/ml.The average recoveries were 99.8% and 99.6%,with RSDs of 1.43% and 1.02%.
The authors' abstract, as published at the source. Chinese Journal of Pharmaceuticals, 2011 · DOI ↗
Continue with a free account
Ask the paper: 3 free questions a day about this paper; save it, get its citation, new summaries every day for your field. Takeaways are Premium.
Continue free on the webSign in with Google or Apple; no card needed. You come back to this paper.
On your phone:
Field: Analytical Chemistry
Analytical ChemistryChemistry