Key papers in Analytical Chemistry

Pofolia’s corpus holds 64 papers from the Analytical Chemistry subfield (2012–2026). The list below starts with the most cited.

Most cited

Ranked by citation count. Because citations accumulate over time, this list naturally leans towards work published a few years ago; for where the field is now, see “recently added”.

  • Principal component analysis: a review and recent developments

    Philosophical Transactions of the Royal Society A Mathematical Physical and Engineering Sciences · 2016 · Q1 · FWCI 128.99 · 9,582 citations · Open access

    Principal Component Analysis (PCA) is a technique that reduces the dimensionality of large datasets by creating new, uncorrelated variables that maximize variance, thereby increasing interpretability while minimizing information loss.

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  • Principal component analysis

    Analytical Methods · 2014 · Q2 · FWCI 73.95 · 2,895 citations · Open access

    Principal component analysis (PCA) is highlighted as a highly significant and potent method within chemometrics and numerous other disciplines.

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  • Advanced Issues in Partial Least Squares Structural Equation Modeling

    2017 · FWCI 67.92 · 2,550 citations

    This practical guide extends foundational PLS-SEM concepts, offering advanced techniques and software examples for researchers to accurately apply and interpret complex structural equation models.

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  • Molecular imprinting: perspectives and applications

    Chemical Society Reviews · 2016 · Q1 · SJR 11.00 · FWCI 159.07 · 2,400 citations · Open access

    Molecular imprinting technology (MIT) creates polymers with tailor-made binding sites for specific molecules, enabling broad applications in separation and sensing.

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  • Management of validation of HPLC method for determination of acetylsalicylic acid impurities in a new pharmaceutical product

    Scientific Reports · 2022 · Q1 · FWCI 205.28 · 2,111 citations · Open access

    A new HPLC method for quantifying salicylic acid and unknown impurities in acetylsalicylic acid tablets (75-150mg) with glycine has been successfully validated according to ICH guidelines.

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  • Fluorescence spectroscopy and multi-way techniques. PARAFAC

    Analytical Methods · 2013 · Q2 · FWCI 37.91 · 2,031 citations · Open access

    A new MATLAB toolbox enhances the application of PARAllel FACtor analysis (PARAFAC) for decomposing fluorescence excitation-emission matrices (EEMs) into chemical components.

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  • Molecularly Imprinted Polymers

    Chemical Reviews · 2018 · Q1 · SJR 16.00 · FWCI 54.28 · 1,587 citations

    Molecularly imprinted polymers (MIPs) are synthetic receptors analogous to natural antibodies, designed to selectively bind target molecules. This review focuses on their application as sensors, where MIPs are coupled with reporting systems (electrical, optical, etc.) to detect analytes.

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  • Textile dyeing industry an environmental hazard

    Natural Science · 2012 · FWCI 11.46 · 1,512 citations · Open access

    The widespread use of synthetic dyes in the textile industry generates highly toxic effluents containing heavy metals, organic compounds, and auxiliary chemicals.

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  • Multivariate Data Analysis

    2025 · FWCI 618.08 · 1,469 citations

    This chapter summarizes multivariate data analysis (MVA) techniques to address the challenge of analyzing large and complex datasets from surface analysis tools like ToF-SIMS.

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  • Blue applicability grade index (BAGI) and software: a new tool for the evaluation of method practicality

    Green Chemistry · 2023 · Q1 · SJR 1.00 · FWCI 172.35 · 1,447 citations · Open access

    A new metric, the Blue Applicability Grade Index (BAGI), is introduced to assess the practicality of analytical methods.

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  • A user-friendly guide to Multivariate Calibration and Classification

    2017 · FWCI 14.89 · 1,413 citations

    This guide offers a non-mathematical introduction to multivariate calibration and classification techniques, specifically tailored for users of near-infrared (NIR) spectroscopy.

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  • Spectroscopic Identification of Organic Compounds

    2020 · FWCI 20.05 · 1,342 citations

    This teaching handout reviews spectroscopic methods for identifying organic compounds, including infrared, mass, and nuclear magnetic resonance spectroscopy.

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  • The Chemistry and Technology of Petroleum

    2014 · FWCI 25.70 · 1,304 citations

    The increasing global demand for petroleum products and evolving environmental regulations are driving the need for new approaches to optimize refinery efficiency and throughput.

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  • Heavy Metal Tolerance in Plants: Role of Transcriptomics, Proteomics, Metabolomics, and Ionomics

    Frontiers in Plant Science · 2016 · Q1 · SJR 1.00 · FWCI 51.06 · 1,296 citations · Open access

    This review synthesizes how advanced 'omics' techniques (transcriptomics, proteomics, metabolomics, ionomics) reveal plant strategies for tolerating heavy metal toxicity.

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  • Partial Least Squares Strukturgleichungsmodellierung

    2017 · FWCI 17.12 · 1,272 citations

    Partial Least Squares Structural Equation Modeling (PLS-SEM) has become a well-established method for estimating causal models in economic and social sciences.

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  • Principal Component Analysis

    Wiley StatsRef: Statistics Reference Online · 2014 · 1,257 citations

    Principal Component Analysis (PCA) is a technique to reduce the dimensionality of large multivariate datasets by replacing original variables with fewer derived variables (principal components) that capture most of the original variability.

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  • Classification tools in chemistry. Part 1: linear models. PLS-DA

    Analytical Methods · 2013 · Q2 · FWCI 28.64 · 1,227 citations

    This tutorial explains the calibration and validation steps for classification models using Partial Least Squares Discriminant Analysis (PLS-DA) in chemistry.

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  • Methylene blue dye: Toxicity and potential elimination technology from wastewater

    Results in Engineering · 2022 · Q1 · SJR 1.00 · FWCI 87.79 · 1,109 citations

    This review synthesizes 240 articles on methylene blue dye (MB) wastewater treatment, highlighting adsorption as a superior elimination method over chemical and biological approaches due to their limitations.

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  • Advances in Asphaltene Science and the Yen–Mullins Model

    Energy & Fuels · 2012 · Q1 · SJR 1.00 · FWCI 61.18 · 1,056 citations

    Recent advances in asphaltene science, utilizing diverse analytical techniques, consistently validate the Yen–Mullins model's description of asphaltene molecular and colloidal structure.

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  • On Splitting Training and Validation Set: A Comparative Study of Cross-Validation, Bootstrap and Systematic Sampling for Estimating the Generalization Performance of Supervised Learning

    Journal of Analysis and Testing · 2018 · Q1 · SJR 1.00 · FWCI 23.87 · 1,025 citations · Open access

    Data splitting method performance for estimating supervised model generalization varies significantly with dataset size; smaller datasets show a notable gap between validation and test set performance across all tested methods.

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Recently added

  • Journal of Analytical Atomic Spectrometry

    Journal of Analytical Atomic Spectrometry · 2026 · Q2 · 257 citations

    This abstract provides no specific research findings, results, or novel contributions. It describes the journal's scope and editorial information.

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  • An Improved Grading System for Measuring Plant Diseases

    Phytopathology · 2025 · Q1 · FWCI 4.90 · 874 citations · Open access

    A novel plant disease grading system is proposed, deviating from equal percentage values to align with the human eye's logarithmic perception of disease severity.

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  • Multivariate Data Analysis

    2025 · FWCI 618.08 · 1,469 citations

    This chapter summarizes multivariate data analysis (MVA) techniques to address the challenge of analyzing large and complex datasets from surface analysis tools like ToF-SIMS.

    Go to source

  • Blue applicability grade index (BAGI) and software: a new tool for the evaluation of method practicality

    Green Chemistry · 2023 · Q1 · SJR 1.00 · FWCI 172.35 · 1,447 citations · Open access

    A new metric, the Blue Applicability Grade Index (BAGI), is introduced to assess the practicality of analytical methods.

    Go to source

  • Methylene blue dye: Toxicity and potential elimination technology from wastewater

    Results in Engineering · 2022 · Q1 · SJR 1.00 · FWCI 87.79 · 1,109 citations

    This review synthesizes 240 articles on methylene blue dye (MB) wastewater treatment, highlighting adsorption as a superior elimination method over chemical and biological approaches due to their limitations.

    Go to source

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