Crystal Growth & Design· 2026Q2
Intramolecular O−H···O Hydrogen Bonding in Crystal Structures of Ortho -Hydroxymethyl-hydroxy (Hetero)arenes
- 0citations
- Q2SCImago
- 2026year
Short summary
Intramolecular O−H···O hydrogen bonds are persistent in crystalline ortho-hydroxymethyl-hydroxy (hetero)arenes, with steric effects playing a significant role in their formation.
AI-generated from the title and abstract; the full text is not read.
Key points
- Intramolecular O−H···O hydrogen bonding is a persistent feature in crystalline ortho-hydroxymethyl-hydroxy (hetero)arenes.
- Steric effects are identified as a significant factor influencing the formation of these intramolecular hydrogen bonds.
- The study combined crystallographic analysis of pyridoxine salts with a database survey of related compounds.
AI-generated from the title and abstract; the full text is not read.
Abstract
Abstract A crystallographic study of pyridoxine salts, combined with a survey of ortho-hydroxymethyl-hydroxy arenes and heteroarenes in the Cambridge Structural Database, was used to evaluate the persistence of intramolecular hydrogen bonding in crystalline ortho-hydroxymethyl-hydroxy (hetero)arenes. The presented analyses suggest that steric effects play a significant role in the formation of intramolecular hydrogen bonds in this class of compounds.
The authors' abstract, as published at the source. Crystal Growth & Design, 2026 · DOI ↗
Continue with a free account
Ask the paper: 3 free questions a day about this paper; save it, get its citation, new summaries every day for your field. Takeaways are Premium.
Continue free on the webSign in with Google or Apple; no card needed. You come back to this paper.
On your phone:
Field: Physical and Theoretical Chemistry
Physical and Theoretical ChemistryChemistry