Chemical Reviews· 2016Q1· Review
The Halogen Bond
- 3,918citations
- Q1SCImago
- 2016year
Short summary
The halogen bond is a directional, non-covalent interaction involving an electrophilic halogen atom and a nucleophilic region, with applications spanning material sciences to drug design.
AI-generated from the title and abstract; the full text is not read.
Key points
- Defines the halogen bond as an attractive interaction between an electrophilic halogen and a nucleophilic region.
- Provides a snapshot of current research and future trends in halogen bond studies.
- Illustrates applications in material sciences, biomolecular recognition, and drug design.
AI-generated from the title and abstract; the full text is not read.
Abstract
The halogen bond occurs when there is evidence of a net attractive interaction between an electrophilic region associated with a halogen atom in a molecular entity and a nucleophilic region in another, or the same, molecular entity. In this fairly extensive review, after a brief history of the interaction, we will provide the reader with a snapshot of where the research on the halogen bond is now, and, perhaps, where it is going. The specific advantages brought up by a design based on the use of the halogen bond will be demonstrated in quite different fields spanning from material sciences to biomolecular recognition and drug design.
The authors' abstract, as published at the source. Chemical Reviews, 2016 · DOI ↗
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Field: Physical and Theoretical Chemistry
Physical and Theoretical ChemistryChemistry