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Journal of Dental Research· 2025Q1· Review

Understanding the Periodontitis–Diabetes Linkage: Mechanisms and Evidence

Dana T. Graves, Michael A. Levine, Sara Aldosary, Ryan T. Demmer

Short summary

Periodontitis treatment reduces HbA1c by ~0.43% in diabetic patients, and emerging evidence suggests periodontitis may drive metabolic dysfunction through systemic inflammation and impaired nitric oxide pathways.

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PeriodonticsDentistry