Lipid Metabolic Reprogramming in Periodontitis-Associated Alveolar Bone Remodeling: Mechanisms, Signaling Pathways, and Therapeutic Implications

Short summary

Periodontitis-associated bone loss is driven by lipid metabolic reprogramming, where physiological lipid metabolism supports bone health, but dyslipidemia and inflammation promote bone loss by increasing harmful lipid metabolites that suppress bone formation and stimulate bone resorption.

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