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Cell Systems· 2026Q1

Mapping the combinatorial coding between olfactory receptors and perception with deep learning

Seyone Chithrananda, Judith Amores Fernandez, Kevin Yang

Short summary

A new deep learning model, MolOR, predicts odor percepts by first mapping odorant molecules to their olfactory receptor (OR) activation profiles, improving percept prediction by 15% and revealing that structurally different molecules with similar smells activate similar OR combinations.

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Field: Sensory Systems

Sensory SystemsNeuroscience