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Genetics· 2026Q1

Sex-specific control of locomotor behavior by neuronal Arhgef10 in aged Drosophila

Mafalda Gualdino, Fabiana Heredia, Alexandra M. Medeiros, Rebeca Zanini et al.

Short summary

Neuronal Arhgef10 loss impairs locomotor behavior in Drosophila, with females showing greater age-dependent decline and males being more sensitive to isoform imbalance, suggesting complex, sex-specific regulation of movement.

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Cell BiologyBiochemistry, Genetics and Molecular Biology