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BMC Pharmacology and Toxicology· 2026Q2

Multinational pharmacovigilance assessment of drug-associated esophageal ulceration and perforation: evidence from FAERS, JADER, and Canada Vigilance

Lihua Zhang, Xinchi Luan, Caiqi Liu, Xiaofei Xin et al.

Short summary

Doxycycline (ROR 41.15), alendronic acid (ROR 21.45), and clindamycin (ROR 18.59) showed the strongest disproportionality signals for esophageal ulceration/perforation in a US FAERS database analysis.

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ToxicologyPharmacology, Toxicology and Pharmaceutics