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Nature Chemical Biology· 2026Q1

Directed evolution of Lantern enables rapid RNA and protein proximity labeling

Yuxin Fang, Ziqi Ren, Fu Zheng, Ruixiang Wang et al.

Short summary

Lantern, an engineered flavoprotein, enables sub-minute RNA and protein proximity labeling in diverse cellular compartments, revealing dynamic molecular organization.

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Cell BiologyBiochemistry, Genetics and Molecular Biology