Proceedings of the National Academy of Sciences· 2026Q1

Local delivery of interferon restores antigen presentation and sensitizes medulloblastoma to T cell killing

Tanja Eisemann, Kendall R. Chambers, Meher Beigi Masihi, Theophilos Tzaridis et al.

0citations
Q1SCImago
2026year

Short summary

Directly delivering interferon-gamma (IFNγ) into medulloblastoma tumors in mice significantly enhanced CD8+ T cell-mediated tumor cell killing and prolonged survival.

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Field: Genetics

GeneticsMedicine