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Nature· 2017Q1

The whole-genome landscape of medulloblastoma subtypes

Paul A. Northcott, Ivo Buchhalter, A. Sorana Morrissy, Volker Hovestadt et al.

Short summary

Whole-genome analysis of 491 medulloblastoma samples identified subgroup-specific driver mutations, including novel actionable targets like KBTBD4 insertions and PRDM6 enhancer hijacking, significantly advancing understanding of this childhood brain tumor.

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Field: Genetics

GeneticsMedicine