Clinical and Translational Gastroenterology· 2026Q1
Cumulative mean pulmonary artery pressure as a marker of hepatic congestion in patients with chronic heart failure
- 0citations
- Q1SCImago
- 2026year
Short summary
Cumulative mean pulmonary artery pressure (mPAP) measured by the CardioMEMS device is associated with hepatic congestion in chronic heart failure patients, outperforming single time-point measurements.
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Key points
- Cumulative mean pulmonary artery pressure (mPAP) is associated with hepatic congestion in chronic heart failure patients.
- The CardioMEMS device was used to collect hemodynamic data for mPAP.
- Hepatic congestion was assessed using MELD-XI score and abdominal imaging.
- Cumulative mPAP showed a stronger association with hepatic dysfunction than cross-sectional measurements.
AI-generated from the title and abstract; the full text is not read.
Abstract
Patients with chronic heart failure (HF) are at increased risk of congestive hepatopathy, yet current clinical markers have limited predictive value. In this proof-of-concept study, we leveraged hemodynamic data from the CardioMEMS device to evaluate the association between pulmonary artery pressure and hepatic congestion, as assessed by MELD-XI score and abdominal imaging findings. We demonstrate that cumulative mean pulmonary artery pressure (mPAP) is associated with MELD-XI score, supporting the potential utility of longitudinal PAP monitoring in estimating hepatic dysfunction. The stronger association observed with cumulative mPAP, compared with cross-sectional measurements, suggests that persistent venous congestion over time may be more relevant to hepatic injury than single time-point value.
The authors' abstract, as published at the source. Clinical and Translational Gastroenterology, 2026 · DOI ↗
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Field: Hepatology
HepatologyMedicine